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ANTI-PARKINSONISM. Complete list of anti Parkinsonism drugs available in Pakistan

Table of list of anti-parkinsonism classes of drug available in Pakistan.
                        1.       Dopamine Agonist

2.       Competitive Inhibitors

3.       Drugs which increase Dopamine release

4.       M.A.O Inhibitors

5.       Synthetic Drugs acting on anticholinergic mechanism


Class
Generic Name
Trade Name
Dosage form
Strength
Dose
Price
ManufactureS
1-Dopamine agonist
Levodopa
Sinemet
Tablets
275 mg
Adult dose:
 100 mg
Single dose:100
Frequency =                        8 hourly

Route = PO
1270.40/ PCK
Merk Sharp & Dhome of Pakistan Ltd.
Aptidopa
Tablets
 250 mg 800/PCK
Bio Lab Ltd.
Sinemet Extra
Tablets
100 mg
838/PCK
OBS Pharma
Bidop
Tablets
 250 mg 800/PCK
Bio Lab Ltd.
Neudopa
Tablets
250 mg
800/PCK
Platinum Pharmaceutical Ltd.
Deiodopa Fort
Tablets
 250 mg 582.02/ PCK
Wilsons Pharmaceutical
Bromocriptine
Brotin
Tablets
2.5 mg
Adult dose:
1.25 to 2.5 mg
Single dose:1.9
Frequency =
12 hourly
Rout = PO                      
303.10/ PCK
Shaigan Pharma (PVT) Ltd.
Cripton
Tablets
 2.5 mg 1025.59/ PCK
EVRON (PVT) Ltd.
Bromocriptine
Tablets
2.5 mg
294.69/ PCK
Medimpex Scientific (PVT) Ltd.
Pergolide
 Celance
Tablets
 o.05 mg
Adult dose:
150 mg
Single dose:150


 291.03/ PCK
ELI LILLY Pakistan (PVT) Ltd

2-COMT Inhibitor
(catechol-o-methyltransferase
Entacapone
OBSONERV
Tablets
20 mg
Adult dose 200mg
Single dose: 200mg
10.36/
PCK
OBS Pharma
3-Drugs  which increase Dopamine release
Amantadine
Amantine
Tablets
100mg
Adult dose 100mg
Single dose: 100
Frequency 24 hourly
Paedriatic dose
2.5-10mg/kg
Singal dose 6.2
Frequency 12hourly
227.00/PCK
Gene-Tech Laboratories
Virofral
Cap
 100mg 265/PCK
English  pharmaceutical
Laboratories
Virofral
Cap
100mg
265/PCK
Biocare  pharmaceutical
PK MERZ
Tablets
 100mg 267/PCK
Brookes  pharmaceutical Laboratories
(PVT)Ltd
4-M.A.O INHIBITOR
Selegiline
Eklin
Tablets
5mg
Adult dose
5-10 mg
Singal dose: 7.5
Frequency 24 hourly
1139.55 /PCK
EVRON (PVT) Ltd
Selgin
Tablets
 5mg 614/PCK
Al-Hameed Agencies (PVT) Ltd
Jumex
Tablets
5mg
735.46/PCK
Searle Pakistan (PVT) Ltd
Juline
Tablets
 5mg 600/PCK
Genome pharmaceutical
(PVT) Ltd

5-Synthetic drugs acting on anticholnergic mechanism
Benzotropine
No brond available


Adult dose
0.007-0.014mg /kg
Single dose 0.01
Frequency 24 hourly


Benzhexol
HEXIDYL
Tablets
2 mg
Adult dose          1-2mg 
Singal dose 1.5mg
Frequency 24 hourly
20.50/PCK
Zafa pharmaceutical laboratories (PVT)Ltd
PACITANE
Tablets
 2 mg 23.70/PCK
PEIZER laboratories Ltd
ZEXOL
Tablets
2 mg
20.00/PCK
USAWA pharmaceutical
Biperiden
 No brond available


Dose 0.014-0.085 mg/kg
Singal dose
0.05
Frequency 8 hourly

Orphendrine
WILGESIC
Tablets
35 mg
Adult dose 100mg Frequency 12 hourly
Singal dose 100
Paedriatic dose
5-13.33mg/kg
Singal dose:9.2
Frequency 8 hourly
         
35.00/PCK
Wilson pharmaceutical
BAKAGESIC
Tablets
 35 mg 35.00/PCK
Searle Pakistan (PVT)Ltd
GENBROL X Forte
Tablets
50 mg
400/PCK
Stanlay  pharmaceutical (PVT)Ltd
GENBROL
Tablets
 50 mg 35.00/PCK
Genix Pharma  (PVT)Ltd
HELIGESIC
Tablets
35 mg
200/PCK
HELICON
NESGESIC
Tablets
 35 mg 205.80/PCK
Pearl pharmaceutical


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